The Concentrating Pipette Select was featured in the April 2018 issue of BioPharm International magazine. The system is particularly useful for biological and particulate contamination monitoring of bacteria, fungal spores, whole cells & viruses including mycoplasma from liquid samples such as ingredients, like water, intermediate products, such as cell culture media, and finished products, including parenteral fluids, and compounded drugs.
InnovaPrep's new Concentrating Pipette Select is featured in Lab Manager Magazine's How it Works feature. The article is posed in a problem / solution format. Problem: Traditional microbiological methods for detecting pathogens involve an enrichment step because the dangerous pathogens are usually very dilute and the volume used for analysis is so small that the threat is often undetectable.
Solution: InnovaPrep’s Concentrating Pipette Select is a small benchtop instrument that allows users to accomplish pathogen concentration and inhibitor removal from large liquid samples with incredible ease and speed....read the entire article to find out how.
The InnovaPrep Concentrating Pipette (CP-150) was compared to standard membrane filtration in a recent study by Hsin-Bai Yina of the University of Maryland, Department of Nutrition and Food Science and Jitendra Patel of USDA, ARS, Environmental Microbial and Food Safety Laboratory. The paper titled, Comparison of methods to determine the microbial quality of alternative irrigation waters was recently published in the Journal of Agriculture Water Management.
The concentrator method was found to be “superior in detecting virulence genes associated with E. coli O157:H7 in creek water. The concentrator method is simple, highly effective, and rapid in detecting bacterial populations in irrigation water and can be used as an alternative to traditional tedious membrane filtration method.”
The below poster presented at Cyto 2017 by Beckman Coulter compares the InnovaPrep Concentrating Pipette to centrifugation, glass filtration, and the PALL Sentino. InnovaPrep outperforms in speed, recovery efficiency, and cost of labor for the detection of bacteria in 1 liter Industrial samples from cooling towers and biopharmaceutical protein production samples.
The US Army Research and Engineering Command report entitled " TECHNICAL EVALUATION OF SAMPLE-PROCESSING, COLLECTION, AND PRESERVATION METHODS" reported on a comparison study of various surface sampling technologies including the InnovaPrep Backpack Surface Sampler, The M-Vac, the BisKit, Copan SRK, and Quicksilver's QS S2P kit and QS S3 swabs. "Overall, the IP Backpack performed the best for sample collection—it was the only device that collected measurable amounts of DNA from each surface tested."
here is a link to the report
InnovaPrep received a contract award this week for a base Indefinite Delivery Indefinite Quantity (IDIQ) under the JE-RDAP program from The Joint Program Executive Office for Chemical and Biological Defense (JPEO-CBD).
Through the JE-RDAP program a key group of highly qualified contractors has been established to compete for Research, Development, Acquisition, and Production/Procurement (RDAP) Orders for future research, development, production/procurement, and fielding of CBRNE defense systems, equipment, and materiel.
JE-RDAP will be a 10 year, Multiple Award, Enterprise-wide, omnibus contract, with a ceiling of $8.27 billion. The InnovaPrep team has expertise and experience in research, development, integration, manufacture, and the commercialization of systems for biosurveillance
Dave Alburty, CEO will be presenting a poster at the upcoming American Association of Aerosol Research meeting entitled: "Devices and Methods for Collection and Concentration of Air Samples for Improved Detection of Microbes on board the International Space Station". The study investigates whether it is possible for a dry filter air sampler to collect viable organisms.
We'll be featuring the new CP-Select at the upcoming PDA Microbiology conference. Stop by for a demonstration!
InnovaPrep is pleased to announce a contract award from The U.S. Army Edgewood Chemical Biological Center (ECBC) subordinate command of the U.S. Army Research, Development and Engineering Command. The nearly $1M 24 month award was in response to Requirement Number: ARMY52-RDECOM09 of the 2016 Rapid Innovation Fund.
InnovaPrep will advance development of ECBC’s prototype Mano Surface Sampler. The prototype Mano is a simple, elegant solution to the need for a surface sampler that can be operated while wearing MOPP gear allowing users to efficiently and quickly collect samples from large surface areas during biosurveillance activities with one hand. The project will include design for manufacturability, development of the manufacturing approaches, and full commercialization of the system for Department of Defense applications. Separate from the sponsored project, InnovaPrep will internally fund additional development, commercialization, and marketing for civilian markets.
The InnovaPrep team has significant talent and expertise in development of systems and consumables for collection and concentration of biological particles from air, surfaces and liquid for biosurveillance activities.
InnovaPrep announces the launch of the Concentrating Pipette Select. The CP Select is the new generation of our popular Concentrating Pipette that was launched in early 2012 with 100 systems in use by leading government, industry, and research labs.
The CP Select is an automated, rapid bio-concentration device for modern microbiology. The system replaces centrifugation and enrichment methods as a front-end to microbial detection. It is highly efficient and effective for bacteria, parasites, molds, fungal spores and fragments, whole cells and viruses.
Fields of application include, but are not limited to: Pharma, water, and consumer products safety; industrial and environmental monitoring; human and animal diagnostic research; and bio surveillance applications.
The new system brings a higher level of efficiency and customization for users.
InnovaPrep’s 30 pending and awarded patents apply to highly effective collection, recovery, and concentration of biological particles from air, surfaces, and liquids. InnovaPrep’s Wet Foam Elution™ process underlies many of these patents and enables recovery of particles from filters, membranes, surfaces, and objects to greatly improve detection of contamination, spoilage organisms, and harmful pathogens.
A continuation has been granted on InnovaPrep’s patented process which underlies the company’s novel ‘Wet Foam Elution’ concentration technologies. The underlying patent entitled, Liquid to Liquid Biological Particle Concentrator was originally awarded in 2008. The continuation patent, number 9738918, was issued on 08/22/17 applying additional claims that further strengthen this patent and adds to the company’s portfolio of 30 awarded or pending patents.
Our Dr. Mike Hornback presented at the American Society of Brewing Chemists conference last month. His presentation entitled: New Tools and Method for Concentration of Spoilage Organisms from American Lager Beers was well received. The study outlines testing performed at InnovaPrep using the new degassing jar and procedure that was recently developed (patent pending). The degassing jars are available now on our web cart.
Dave Alburty, InnovaPrep CEO, will be leading the Rapid Sample Preparation for Pathogen Detection workshop for the upcoming Biodetection Technology track at the BioDefense World Summit in Alexandria, VA later this month.
We are pleased to announce a new distribution partnership with Central Scientific Commerce (CSC), who will be marketing and supporting InnovaPrep products in Japan. CSC serves universities, national and public laboratories, laboratory hospitals and inspection centers, and private companies (pharmaceutical, food, chemical, and cosmetics). Currently CSC has 4 offices in Japan, Tokyo, Osaka, Fukuoka and Sapporo, to cover the entire Japanese market.
Andy Page, InnovaPrep president and CTO will be presenting at the upcoming Water Microbiology conference at UNC Chapel Hill. The session is "Macro to Micro Interface-Existing Approaches" and he will also be part of a panel discussion on "Scaling the technical and political hurdles to successful molecular method implementation for water quality management".
InnovaPrep will be attending, exhibiting and presenting at upcoming meetings this summer. Here is a brief summary. More info to come soon
InnovaPrep was recently featured in Kansas City Public Television show called "Show-Me Innovations".
Catch a brief look into the InnovaPrep facilities and hear interviews with CEO, Dave Alburty and President and CTO Andy Page .
Under our ongoing NASA project, InnovaPrep has been adapting its concentration technology for zero gravity. The purpose of the development is rapid microbial testing of the
potable water supply on board the International Space Station. A sample concentration prototype has been built and was tested this month by InnovaPrep engineers Zach Packingham and Alec Adolphson aboard a weightless flight (parabolic flight aka "vomit comet") on ZERO-G's G-FORCE ONE. They had a series of 30 second intervals of weightlessness to perform the carefully choreographed test series. The testing was successful. The next step is testing aboard the ISS, though it has not yet been scheduled.
InnovaPrep made the list for Kansas City Companies to Watch in 2017 according to KC Sourcelink, they state we are the movers and shakers who are turning disruptive ideas into sought-after businesses. Companies on the annual KC Watch List received funding, grant or investment, in 2015 and 2016, or two investments or grants in 2016.
InnovaPrep was just awarded their third patent for 2017. This is number 12 of awarded patents of the 29 total patent applications the company has filed surrounding their core technology, Wet Foam Elution. The patent, Titled: Liquid to Liquid Biological Particle Concentrator with Disposable Fluid Path (a continuation), was awarded March 17th. The patent number is, 9,593,359.
I&L Biosystems has represented InnovaPrep in Germany, France, and Benelux for two years now and has been an exceptional partner providing excellent service for our customers. We are extremely pleased they have now expanded their enterprise to the UK and Spain. Please see our International Distributors list for more information.
Another New Patent! 2nd Award this Year; issued 2/21/17 Patent # 9574977 "Liquid to Liquid Biological Particle Concentrator with Disposable Fluid Path" relates to InnovaPrep's flagship product, The Concentrating Pipette, and its consumables. Inventors include: Andy Page, CTO; Zachary Packingham, Design Engineer; Dave Alburty, CEO; Alec Adolphson, Staff Engineer.
InnovaPrep patent application 14/084,403 was awarded January 3, 2017. Patent Number 9534989 entitled, Devices, Systems and Methods for Elution of Particles from Flat Filters applies to existing InnovaPrep technologies and technologies in the development pipeline.
This is the 8th patent awarded of the total 23 that InnovaPrep has filed to date.
Inventors include Andy Page, President and CTO; Dave Alburty, CEO; Pam Murowchick; Zachary Packingham, Design Engineer; and Alec Adolphson, Engineering Technician.
A New White Paper is available entitled, "Microbial Monitoring of Air, Surfaces, and Liquids in Food Processing Environments" describing how InnovaPrep's rapid sample collection and concentration tools can dramatically help improve detection of foodborne threats in air, surface, and liquid samples.
When paired with Rapid Microbial Methods (RMM’s) of analysis, these technologies offer a truly rapid, comprehensive, yet streamlined monitoring program without incubation steps.InnovaPrep technologies are highly suited for:
A new research article published in the ASM mSphere Journal by University of Wisconsin—Madison and the Biotechnology and Planetary Protection Group, at the NASA Jet
Propulsion Laboratory describes Microbial Observatory Experiments on the International Space Station (ISS) using a method of recovering surface samples that included the InnovaPrep Concentrating Pipette. The aim was to gain a better understanding of how fungi may adapt to microgravity and how this may affect interactions with humans in a closed habitat.
The study outlines an efficient method for collecting samples from large area surfaces. In summary, a pre-wetted 9”x9” polyester wipe using sterile water was used to sample a 1 meter squared area. The wipe was then transferred to a to a 500-ml sterile bottle containing 200 ml of sterile PBS. The bottle with the wipe was shaken for 2 min followed by concentration with the InnovaPrep Concentrating Pipette. To view the publication, please follow this link: http://msphere.asm.org/content/msph/1/5/e00227-16.full.pdf
In a separate project, InnovaPrep is developing new Devices and Methods for Collection and Concentration of Air and Surface Samples for Improved Detection funded by a NASA SBIR.
InnovaPrep was selected via a competitive process for the National Institutes of Health Commercialization Accelerator Program (CAP), a program designed to help some of the agency’s most promising small life science and healthcare Phase II awardees develop commercial business and transition their SBIR/STTR-funded technologies into the marketplace. The CAP provides selected participants with individualized assistance through individual mentoring and consulting sessions, training workshops, and access to domain experts. This is in regards to InnovaPrep's Phase II FDA award for the high-flow hollow fiber Concentrating Pipette Tip development.
Dave Alburty, InnovaPrep CEO, will be presenting a poster at the upcoming American Association for Aerosol Research conference in Portland, OR.
The poster, entitled “Comparison Retention Efficiency and Collection Efficiency Testing on two Generations of the SpinCon Advanced Air Sampler” contains the results of testing performed on the newly released model of the SpinCon, the SpinCon® II Advanced Air Sampler. The redesigned model provides the same capabilities as before with added improvements including a more powerful blower, removable components for ease of integration, among other design changes.
This comparison testing was designed to mirror the testing performed originally at Midwest Research Institute (now MRIGlobal) during the development of the SpinCon technology as well as testing performed at U.S. Army Edgewood Chemical Biological Center (ECBC).
InnovaPrep is pleased to announce a Phase II subcontract award from its partner, ENSCO, Inc., prime contractor for the SenseNet Program on behalf of the U.S. Department of Homeland Security Science & Technology Directorate. The goal of the DHS SenseNet Project is to develop and demonstrate a tiered aerosol detection sensor architecture that combines low cost and rapid dedicated environmental monitoring detectors with newly emerging commercial sensors that will be utilized by citizens and facility owners for air quality, pollution tracking, and building efficiency purposes....
A research article entitled, Longitudinal Metagenomic Analysis of Hospital Air Identifies Clinically Relevant Microbes (King, et al.) was recently published on PLOS ONE.
The sampling in the study was performed with an ACD-200 Bobcat Air Sampler that was customized for this important study funded by the Department of Homeland Security.
Dr. Mike Hornback, InnovaPrep Senior Scientist, will be presenting a poster at the upcoming International Association for Food Protection conference in St. Louis.
The poster, entitled “Concentration of Escherichia coli O157:H7 from Experimentally Infected, Pre-Packaged Spinach by InnovaPrep’s Concentrating Pipette” contains the results of a trial study to develop a new method permitting the detection of Escherichia coli O157:H7 in spinach within a single work-shift using a reduced enrichment time, followed by mechanical concentration of the enriched fluid using the InnovaPrep Concentrating Pipette and detection using real-time quantitative Polymerase Chain Reaction (qPCR).
We are pleased to announce a new distribution partnership with MALVA S.A.. who will be supporting InnovaPrep products in Greece. Since its establishment in 1988, Malva S.A. has been the leading provider of cutting-edge technologies in analytical and quality control laboratories and in Academia across Greece and abroad.
Director of Business Development, John Payne will be delivering a presentation entitled, Methods and Devices for Rapid Concentration of Waterborne Pathogens from Surface Waters for use with Rapid Molecular Methods at the Water Microbiology & Novel Tech conference located in Chicago next week.
We are pleased to announce a new distribution partnership with SPD Scientific Pte Ltd. who will be supporting InnovaPrep products in Singapore and including Malaysia and Thailand. SPD Scientific is part of the Biomedia Group that provides a wide range of biomedical and laboratory equipment, reagents, test-kits, laboratory consumables, as well as diagnostic products. The company serves industries such as healthcare, academic and government research institutions, pharmaceutical and food and beverage, by providing them with the appropriate tools that aid them in their research and discoveries.
CEO Dave Alburty will be co-leading a special session entitled, RAPID SAMPLE PREPARATION FOR PATHOGEN DETECTION to be held on Tuesday, June 28, 2016 | 5:30 – 8:30pm as part of Biodefense World Summit. Please follow the link for more details about the work shop http://www.biodefenseworldsummit.com/content.aspx?id=194
A second phase Small Business Innovative Research (SBIR) grant from NASA has been awarded InnovaPrep to continue the work done during the Phase I project, which showed the feasibility adapting the InnovaPrep bio-concentration technology to work in a microgravity environment. The developed system is slated for use aboard the International Space Station (ISS) for the purpose of monitoring the safety of the ISS water supply http://sbir.gsfc.nasa.gov/SBIR/abstracts/15/sbir/phase2/SBIR-15-2-H3.01-9921.html
In addition, a new Phase I NASA project has been awarded InnovaPrep for Devices and Methods for Collection and Concentration of Air and Surface Samples for Improved Detection. This project builds on current collection and concentration technologies utilizing the company’s patented wet foam elution process. http://sbir.nasa.gov/SBIR/abstracts/16/sbir/phase1/SBIR-16-1-H3.01-7134.html
Andy Page, President and Chief Technology Officer will be presenting a poster at the upcoming EPA's Recreational Waters Conference April 12-15th in New Orleans. The poster addresses rapid detection of fecal indicator bacteria in recreational waters.
The InnovaPrep concentration and wet foam elution processes will be presented along with developmental and commercially available InnovaPrep concentration systems. Data from use of the Concentrating Pipette system for concentration of indicator bacteria from recreational waters and detection by quantitative Polymerase Chain Reaction will be presented, including concentration efficiencies, concentration factors, and detection limits. Read the White Paper here.
Rapid analytical methods are becoming an essential part of a complete program for Microbiological Control and Monitoring of Aseptic Processing Environments, however, widespread use of these technologies is long overdue. The ability to reduce ”time-to-detection" from days to same-shift will provide widespread benefits through reduction in holding times, recalls, and incidence of harm. In addition, the adoption of rapid methods allow new sampling regimes to be more meaningful, effective, and informative for corrective action. These are significant changes that will make pharmaceutical products safer and protect the industry from losses in revenue.
To fully realize the promise of next-generation rapid analytical methods, new collection and sample prep technologies will also need to be adopted. more
We are pleased to announce a new distribution partnership with I&L Biosystems GmbH who will be supporting InnovaPrep products in western Europe. I&L Biosystems GmbH serves Germany, Switzerland, and Austria, along with its sister companies, I&L Biosystems France SAS, and L.A. BioSystems B.V. serving Belgium, The Netherlands, and Luxembourg. Their focus is on sales and distribution of high quality laboratory equipment, including InnovaPrep’s Concentrating Pipette to customers and researchers in the microbiology, cell biology, and biotechnology markets.
InnovaPrep’s Dry Filter BioAerosol Sample Collector with Rapid Filter Elution Kit has become the collector of choice for major systems integrators for Department of Defense programs such as the Joint Biological Tactical Defense System (JBTDS) and the Joint United States Forces Korea Portal and Integrated Threat Recognition, known as JUPITR. The integratable collectors incorporate the collection module and filter elution kit of the company’s commercial ACD-200 Bobcat Air Sampler. The components were chosen for their high collection efficiency, ease of integration into larger monitoring systems, and ease of effective sample recovery in tactical environments using the company’s patented Wet Foam Elution method.
Under a Phase 1 NASA Small Business Innovative Research (SBIR) Grant, InnovaPrep is adapting its bio-concentration technology to work in a microgravity environment. The developed system is slated for use aboard the International Space Station (ISS) for the purpose of monitoring the safety of the ISS water supply.
For the project, InnovaPrep Engineer, Alec Adolphson, recently traveled to Portland State University to to work along with Oregon-based company, IRPI LLC, to test the modified device using the 5-story Dryden Drop Tower. more ...
InnovaPrep was founded in 2009 as a manufacturing company based on an invention developed in our Sister company AlburtyLab. AlburtyLab is an independent research lab located in Drexel MO that primarily deals with, but is not limited to, aerosol research projects. The lab has a recirculating wind tunnel with a sealed test chamber. The test chamber is used to test among other things air inlets, air sampling devices and air monitoring equipment.
Dave Alburty, CEO, will be co-instructing a workshop titled, RAPID SAMPLE PREPARATION FOR PATHOGEN DETECTION at the upcoming Biodefense World Summit in Bethesda, MD.
This workshop will discuss sample preparation technologies for detection, identification and analysis of biomedical, biological and chemical agents, biothreats in point-of-care, laboratory and field settings. It will review the novel and rapid technologies for sample preparation, application of analytical strategies and automation in biodetection.
InnovaPrep was recently awarded a Phase I Small Business Innovative Research Grant from NASA for A Rapid Concentration System for Improved Detection of Microbes in International Space Station Potable Water. Work will begin immediately to apply the InnovaPrep concentration technology using Wet Foam Elution for use in zero gravity applications. InnovaPrep has earned a total of four Phase I and two Phase II SBIR awards.
InnovaPrep CEO, Dave Alburty will host a lively presentation entitled, Aerosol Sampler Selection Criteria: Next generation tools for bioaerosol collection and microbe concentration, on the pros and cons of modern aerosol collection technologies as we address the emerging needs of aerosol science. Case studies will be presented including wet and dry collection methods as well as determining sampling efficiency.
InnovaPrep's President and Chief Technology Officer, Andy Page was selected to deliver a verbal presentation at the upcoming Water Microbiology Conference 2015 at the University of North Carolina at Chapel Hill. The presentation is entitled, “Concentration of Microorganisms by Concentrating Pipette and Wet Foam Elution”.
The InnovaPrep SpinCon® II Advanced Air Sampler provides the same capabilities as before with added improvements including a more powerful blower and ruggedized carrying case with built-in storage for sampling supplies. In addition, the collector module and controls module can be easily removed from the case to provide ultimate versatility for the user.
The SpinCon II is ideally suited for the collection of bioaerosols, particulate matter, and soluble vapors, including submicron-sized particles, airborne molecular contamination, biological particulates, and volatile and semivolatile chemical compounds. The system addresses a broad range of advanced air sampling requirements and is the gold standard for collecting large quantities of airborne pathogens. more information
InnovaPrep is excited to announce the release of four new pipette tips for the Concentrating Pipette that greatly expand the applications for the device. The new high-flow tips are made with bundles of hollow fiber filters that will allow higher flow, larger starting sample volumes, smaller final extract volumes, and allow difficult matrices to be concentrated. In addition, two ultrafiltration tips are now offered for virus concentration.
The new pore sizes include 0.45µm and 0.2 µm for high-flow concentration of bacteria, whole cells, spores, pollen, and parasites. As well as a 0.05 µm and an ultrafiltration tip for virus concentration. More information
Drexel, MO (November 19, 2013) – InnovaPrep LLC is pleased to announce the award of two new patents applying specifically to processes and consumable components of InnovaPrep’s Concentrating Pipette and ACD-200 Bobcat Air Sampler. The company holds a family of 15 awarded and pending patents surrounding InnovaPrep’s underlying technology termed “Wet Foam Elution” awarded in 2012. The process is utilized in many of the Company’s currently available and pipeline products and greatly improves the way biological samples, especially those containing pathogenic organisms, are collected and prepared for analysis. U.S. Patent Application No. 61/276,737, entitled "A Liquid to Liquid Biological Concentrator with Disposable Fluid Path”, was issued November 19, 2013 as U.S. Patent No. 8,584,535. This patent is owned by InnovaPrep and applies specifically to the Concentrating Pipette’s single-use disposable filter tips and other pipeline products. U.S. Patent Application No.61/277,119, entitled "Devices, Systems, and Methods for Elution of Particles from Flat Filters”, was issued November 19, 2013 as U.S. Patent No. 8,584,536. This patent is owned by InnovaPrep and applies specifically to the ACD-200 Bobcat Dry Filter Air Sampler’s (including integratable models) single-use Rapid Filter Elution Kit and other pipeline products.
Pipeline Selects Dave Alburty for 2013 Entrepreneurial Fellows Program
CEO of Drexel, MO based InnovaPrep chosen to participate in nationally recognized year-long program designed to accelerate the growth of high-performance entrepreneurs.
Drexel, MO January 25, 2013— The Pipeline entrepreneurial fellowship program has announced that Dave Alburty, CEO of InnovaPrep, will join the 2013 Class of Entrepreneurial Fellows. Pipeline is an exclusive community of high-potential entrepreneurial leaders building high-growth companies throughout the Midwest Region. More
Lab Manager Magazine article 2012 on the Concentrating Pipette. Link
InnovaPrep LLC is pleased to announce that U.S. Patent Application No. 12/131,015, entitled "A Liquid to Liquid Biological Particle Concentrator”, was issued February 7, 2012 as U.S. Patent No. 8110112. This patent is owned by InnovaPrep, and applies to a rapid one-pass liquid filtration system that efficiently concentrates biological particles including proteins/toxins, viruses, DNA, and/or bacteria. Concentration of these particles is advantageous for detection because concentrating them into a small volume makes them easier to detect.