Biomarker Discovery & Diagnostics

Streamline Concentration, Isolation and Purification of Biological Particles - from Viruses to Cell Fragments, Extracellular Vesicles (EVs), Mammalian and Bacterial Cells, 

Enabling Detection and Quantification of Disease Biomarkers and Drug Candidates for Advanced Diagnostic Assays and Drug Discovery.

In the pursuit of precision medicine, the identification and analysis of biomarkers are essential to early disease detection, treatment monitoring, and therapeutic innovation. InnovaPrep’s technologies offer unmatched efficiency and ease in isolating and concentrating a wide range of biological particles—from bacteriophages and cell fragments to extracellular vesicles (EVs), mammalian cells, and microorganisms—from diverse and often complex sample types.

 

InnovaPrep Technology Advances Discovery and Diagnostics

  • Exosome and EV Isolation - gentle process preserves integrity
  • Liquid Biopsy - exponential concentration boosts sensitivity
  • Infectious Diseases - rapid target concentration from air to wastewater
  • Phage Discovery - supports diagnostics, AMR research & phage therapy

Our solutions help researchers and clinicians accelerate discoveries in cancer diagnostics, infectious disease monitoring, and personalized medicine. By streamlining workflows, reducing processing times, and boosting assay sensitivity, InnovaPrep’s technologies make biomarker-driven approaches more efficient and reliable.

applications & uses

Scientific Information

We’re thrilled to announce that InnovaPrep has been selected by BioTools Innovator,  as one of the Top 31 Life Science Tools and Diagnostics Companies for their 2025 cohort! BioTools Innovator is the first ever accelerator focused on Life Science research tools.

This prestigious selection places us among an elite group of innovators driving advancements in diagnostics, therapeutics, and life science research.

Scientific Information
The Concentrating Pipette was used to isolate and concentrate bacteriophage used as a therapeutic approach to combat infections caused by antimicrobial-resistant bacteria in cystic fibrosis patients. “The main advantage of the Concentrating Pipette was that it allowed us to easily concentrate a large sample volume (900 mL), which can be difficult to manage with traditional methods such as ultracentrifugation”,
Scientific Information
The aim of this testing was to investigate ways to replace or optimize upon the widely used ultracentrifuge method for isolating exosomes (Extracellular Shed Vesicles) for basic science applications as the high forces generated using ultracentrifugation can negatively affect exosome morphology by impacting exosome function - and thus a gentler process of isolation is needed.

What sets us apart

Gentle Process

Maintains integrity of cells and viruses, enabling viable studies and culture.

Versatile Applications

Ideal for broad range of samples, targets and use cases. 

Streamlined workflows

Simple workflow with consistent, reliable results

The concentrating pipette may be a faster alternative method to isolate exosomes with performance comparable to ultracentrifugation.

Fong et Al. Lawrence Livermore National Lab 

Related Products

CP Select™ Concentrating Pipette

Experience the efficiency of the FluidPrep™ Concentrating Pipette System by InnovaPrep, engineered to simplify workflows and boost assay sensitivity. This system is highly effective in recovering microorganisms and particles, including bacteria, parasites, molds, fungal spores, whole cells, viruses, and synthetic particles, from sample volumes between 0.5 mL and 5 L.

The one-pass method uses robust filtration followed by instant sample recovery using InnovaPrep's patented Wet Foam Elution™ process delivering a highly concentrated sample ideal for detection by culture, PCR, sequencing, and more – with unprecedented speed and efficiency. For applications needing rapid, reliable sample concentration, this system provides a faster, simpler alternative to traditional culture enrichment, centrifugation, and ultracentrifugation methods.

Includes: 

  • CP Select Instrument
  • Accessory Kit  -  Includes the Storage Fluid Adapter, Permeate Line, Maintenance Tip
  • One-year manufacturer warranty

Consumable supplies (pictured) and optional accessories sold separately.

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FluidPrep™ Elution Buffer (CP Select™)

For use with CP Select™ only

 

Optimize the performance of your FluidPrep™ Concentrating Pipette System with our specially formulated Elution Buffers. Designed to enhance concentration efficiency through our patented Wet Foam Elution™ process, choosing the right elution buffer ensures optimal recovery, target integrity, and seamless compatibility with downstream applications. Use our guide to select the best elution buffer for your specific needs.

Note:
PBS, PBS-X and Tris Elution Fluids are irradiated and have min. of 90 days shelf-life at time of shipment. 
DMEM Elution Fluid is available in a 5-pack only, is non-irradiated. Store refrigerated.

 

Expert Support - If you need assistance in selecting the most suitable CPTs and elution buffer for your CP Select system, our team of experts is ready to help. Contact us for tailored advice and support to ensure optimal performance and results.

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FluidPrep™ Mini CPT - Irradiated

Single-use, Irradiated, Mini Concentrating Pipette Tips (CPTs) are available in a variety of formats. Selecting the ideal CPT for use with the FluidPrep Concentrating Pipette System is crucial to achieving optimal performance - both in terms of speed and concentration factor of your target. 

 

Selecting the Right CPT - Factors to consider

1 - Pore Size based on Nature and Size of Target Particle

CPTs are available in four pore sizes – Ultra, 0.05 µm, 0.2 µm, and 0.45 µm to accommodate the wide range of target particle types and sizes. 

*Volume and flow rates will vary by matrix and selected menu settings

2 - Surface Area by Sample Matrix and Sample Volume

The complexity of your sample and overall volume to be processed will influence the speed and overall volume that can be processed effectively. Two options are available.

  • Standard length CPTs - Membrane surface area is 98 cm² nominal. Recommended for sample volumes over 200 mL and/or more complex or turbid matrices.
  • Mini 25 CPTs  - The membrane surface area is 25 cm² nominal and capable of smaller elution volumes with optimized menu settings. Recommended for sample volumes 200 mL or less and of low complexity/turbidity. Short-walled sample containers and the CP Sample Carousel are required for use.

As a general Rule of Thumb, we recommend using the smallest tip that provides the desired concentration factor for your application.

3 - Packaging Format by Target Application

All products are produced aseptically in a cleanroom environment. Understanding your downstream application will help identify which package format is best suited.

  • Non-irradiated CPTs -Bulk packaged and suitable for most applications due to the inherent low background.  Recommended if target organisms are non-ubiquitous or using selective assays.
  • Irradiated CPTs  - Individually wrapped and irradiated to provide added protection against bioburden. Best for culture-based downstream applications.

Tips are designed for use with the CP Select (sold separately) 

We recommend use with the CP sample carousel item #HC08042, and our selection of short-walled sample containers, Sample Cup Flip-Top 200ml item #HC08040-10, Sample Vial Flip-Top 10 mL item # HC08041-10, and Sample Cup with Conical Bottom item #AC08106-10.

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Application Notes 

Explore our detailed application notes to learn how you can use our innovative solutions to optimize your sample processing. 

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Research Highlights

Explore research highlights to learn more about how clients use our products.

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