CP Select™ Clarification & Concentration Consumable Selection Guide

Select the Right Consumables for Your Sample Preparation Workflow

The FluidPrep™ CP Select™ platform supports a wide range of sample preparation workflows through the use of Concentration Tips (CPTs), CPT Matrix Prefilters, Upstream Clarification Filters, and Elution Fluids.

Different samples present different challenges. Some samples can be processed directly using a Concentration Tip, while others may benefit from clarification to improve processability, reduce fouling, increase throughput, or support downstream analysis.

This guide provides an overview of the primary concentration and clarification consumables available for CP Select workflows.

For detailed CPT selection guidance, download the Concentration Tip (CPT) Selection Guide

Concentration Tips (CPTs)

Concentration Tips are the primary consumable used during CP Select processing. The CPT retains target material during concentration and works together with patented Wet Foam Elution™ technology to produce a small-volume analysis-ready sample.

Available CPT families include:

  • Ultra CPT
  • 0.05 µm CPT
  • 0.2 µm CPT
  • 0.45 µm CPT
  • Mini 25 CPTs

Selection depends on the target, sample matrix, workflow objectives, and downstream analytical method.

View Concentration Tips

 

Clarification Options

Not all samples require clarification.

However, samples containing debris, fibers, sediment, suspended solids, aggregates, or other matrix material may benefit from clarification before or during concentration.

Clarification approaches can range from settling, screening, filtration, or centrifugation to workflow-specific consumables designed for use with the CP Select platform.

InnovaPrep offers two clarification product families specifically designed to support CP Select workflows.

 

Upstream Clarification Filters

Upstream Clarification Filters are used before concentration begins.

These products help reduce matrix material before the sample enters the CP Select workflow and may be useful when processing samples containing coarse debris, sediment, fibers, or persistent suspended particulates.

Available options include:

100 µm Mesh Upstream Clarification Filter

Designed to remove larger debris and coarse particulates.

1 µm Upstream Clarification Filter

Designed to reduce fine particulates and suspended material before concentration.

Best suited for workflows where clarification is performed as a separate step before concentration.

View Upstream Clarification Filters

 

CPT Matrix Prefilters

CPT Matrix Prefilters attach directly upstream of a Concentration Tip and function during active CP Select processing.

Unlike Upstream Clarification Filters, CPT Matrix Prefilters provide simultaneous clarification and concentration within a single workflow.

Available pore sizes include:

  • 1 µm
  • 8 µm
  • 25 µm
  • 75 µm

Potential benefits may include:

  • Improved processability
  • Reduced fouling
  • Increased throughput
  • Improved handling of challenging matrices

Important

CPT Matrix Prefilters must be removed before Wet Foam Elution™ is performed.

View CPT Matrix Prefilters

CPT Attached Matrix Prefilter Quick Guide – InnovaPrep

 

Elution Fluids

Following concentration, retained material is recovered using patented Wet Foam Elution™ technology.

Available Elution Fluids include:

  • PBS
  • PBS-X
  • Tris
  • DMEM

Additional formulations may be available depending on workflow requirements.

View Elution Fluids

 

Quick Comparison

Product Type

Primary Function

Typical Use

Concentration Tips (CPTs)

Retain target material during concentration

All CP Select workflows

Upstream Clarification Filters

Reduce matrix material before concentration

Clarification performed before concentration

CPT Matrix Prefilters

Simultaneous clarification and concentration

Challenging matrices requiring additional processability

Elution Fluids

Recover retained material after concentration

Wet Foam Elution™ recovery

Related Resources

  • FluidPrep™ Consumable Selection Guide
  • CP Select™ Instrument Specification Sheet
  • CP Select™ Instrument User Guide & Operating Manual
  • CPT Matrix Prefilter Quick Guide
  • CP Select™ Set-Up and Training Videos

Need Help Selecting Consumables?

Contact InnovaPrep for assistance selecting Concentration Tips, CPT Matrix Prefilters, Upstream Clarification Filters, and Elution Fluids for your specific sample preparation workflow.

CP Select™ Concentration Tip, Matrix Prefilter & Clarification Filter Selection Guide

Select the Right Consumables for Your Sample Preparation Workflow

The FluidPrep™ CP Select™ platform supports a wide range of sample preparation workflows through the use of Concentration Tips (CPTs), CPT Matrix Prefilters, Upstream Clarification Filters, and Elution Fluids.

Different consumables serve different functions within the workflow. Selecting the appropriate consumables can improve processability, reduce fouling, increase throughput, support target recovery, and enhance downstream analytical performance.

Whether processing environmental, wastewater, food and beverage, clinical, bioprocess, or life science research samples, understanding the role of each consumable helps build more effective workflows.

[Download FluidPrep™ Consumable Selection Guide]

What Are You Trying to Process?

Water and Environmental Samples

  • Drinking water
  • Surface water
  • Groundwater
  • Recreational water
  • Environmental monitoring samples

Wastewater Samples

  • Influent
  • Effluent
  • Sewer monitoring samples
  • Wastewater surveillance samples

Food and Beverage Samples

  • Produce rinses
  • Carbonated beverages
  • Dairy products
  • Process water
  • Ingredient and manufacturing samples

Clinical and Research Samples

  • Plasma
  • Serum
  • Urine
  • Cell culture fluids
  • Extracellular vesicle preparations

Different sample types may benefit from different concentration and clarification consumables depending on matrix characteristics, target abundance, solids content, and downstream analytical requirements.

Common Target Categories

Biological Targets

  • Viruses
  • Bacteria
  • Fungi
  • Protozoa
  • Phage

Cellular and Vesicle Targets

  • Mammalian cells
  • Extracellular vesicles (EVs)
  • Exosomes

Environmental and Particulate Targets

  • Environmental DNA (eDNA)
  • Microplastics
  • Spores
  • Pollen
  • Particle-associated biomarkers

Understanding the Workflow

The FluidPrep™ CP Select™ platform supports a wide range of sample preparation workflows through the use of Concentration Tips (CPTs), CPT Matrix Prefilters, Upstream Clarification Filters, and Elution Fluids.

Different consumables serve different functions within a workflow. Depending on the sample, target, matrix characteristics, and analytical objectives, users may employ concentration alone or incorporate clarification steps before or during concentration.

Not all samples require clarification. Some samples can be processed directly using a Concentration Tip, while others may benefit from additional matrix management to improve processability, reduce fouling, increase throughput, or support downstream analytical performance.

Understanding the role of each consumable category helps users select appropriate tools for their specific application and workflow objectives.

Step 1: Select a Concentration Tip (CPT)

Concentration Tips are the primary consumable used during CP Select processing.

The CPT retains target material during concentration and works together with Wet Foam Elution™ recovery to produce a small-volume analysis-ready sample.

Standard CPTs

Standard CPTs provide approximately 98 cm² of membrane surface area and are typically used for larger sample volumes and more challenging matrices.

Available options include:

  • Ultra CPT
  • 0.05 µm CPT
  • 0.2 µm CPT
  • 0.45 µm CPT

Mini 25 CPTs

Mini 25 CPTs provide approximately 25 cm² of membrane surface area and are generally used for:

  • Smaller sample volumes
  • Lower-solids samples
  • AirPrep™ eluates
  • Low-turbidity waters
  • Other lower-complexity matrices

View CP Select™ Concentration Tips

Step 2: Determine Whether Clarification Is Needed

Samples containing debris, fibers, solids, aggregates, colloids, or other matrix material may benefit from clarification.

Clarification may help:

  • Improve processability
  • Reduce fouling
  • Increase throughput
  • Improve workflow consistency
  • Support downstream analytical performance

The appropriate clarification approach depends on the sample matrix, target of interest, solids content, processability requirements, and downstream analytical method.

Numerous clarification approaches may be appropriate depending on the application, including:

  • Settling
  • Screening
  • Sieving
  • Mesh filtration
  • Bag filtration
  • Cartridge filtration
  • Centrifugation
  • Upstream Clarification Filters
  • CPT Matrix Prefilters

The following products are designed specifically for integration with CP Select workflows.

Upstream Clarification Filters

Upstream Clarification Filters are used before concentration begins.

These products reduce matrix material before the sample enters the CP Select workflow.

Available Options

100 µm Mesh Upstream Clarification Filter

Designed to remove larger debris and coarse particulates.

Common examples include:

  • Plant material
  • Fibers
  • Sediment
  • Gross solids

1 µm Upstream Clarification Filter

Designed to reduce persistent fine particulates and suspended material.

May be useful when processing samples containing:

  • Fine solids
  • High turbidity
  • Persistent suspended particulates

Workflow Position

Sample

↓

Upstream Clarification Filter

↓

CP Select™

View Upstream Clarification Filters

CPT Matrix Prefilters

CPT Matrix Prefilters attach directly upstream of a Concentration Tip and function during active CP Select processing.

Unlike Upstream Clarification Filters, CPT Matrix Prefilters provide simultaneous clarification and concentration.

Available pore sizes include:

  • 1 µm
  • 8 µm
  • 25 µm
  • 75 µm

Potential benefits may include:

  • Improved processability
  • Reduced fouling
  • Increased throughput
  • Improved handling of challenging matrices

Workflow Position

Sample

↓

CPT Matrix Prefilter

↓

Concentration Tip

↓

CP Select™

Important

CPT Matrix Prefilters must be removed before Wet Foam Elution™ is performed.

View CPT Attached Matrix Prefilters

Download CPT Attached Matrix Prefilter Quick Guide

Step 3: Select an Elution Fluid

Following concentration, retained material is recovered using patented Wet Foam Elution™ technology.

The CP Select platform supports multiple Elution Fluid options.

Common examples include:

Elution Fluid

Typical Uses

PBS

General recovery workflows

PBS-X

Enhanced recovery workflows

Tris

Molecular biology workflows

DMEM

Cell and biological workflows

Custom formulations may also be available.

View Elution Fluids

Quick Comparison

Product Type

Primary Function

Used Before Concentration

Used During Concentration

Upstream Clarification Filters

Reduce matrix material before processing

Yes

No

CPT Matrix Prefilters

Simultaneous clarification and concentration

No

Yes

Concentration Tips (CPTs)

Retain target material

No

Yes

Elution Fluids

Recover retained material

No

Recovery Step

Frequently Asked Questions

What is the difference between a CPT Matrix Prefilter and an Upstream Clarification Filter?

Upstream Clarification Filters are used before concentration begins to reduce matrix material before the sample enters the CP Select workflow.

CPT Matrix Prefilters attach directly to a Concentration Tip and function during active sample concentration.

Do all samples require clarification?

No. Many samples can be processed directly using a Concentration Tip without clarification.

Clarification is typically considered when samples contain debris, solids, fibers, aggregates, or other matrix material that may affect processability.

Can CPT Matrix Prefilters be used with all Concentration Tips?

Yes, CPT Matrix Prefilters are designed for use with compatible CP Select Concentration Tips. Refer to current product documentation for compatibility information.

What Elution Fluid should I use?

Elution Fluid selection depends on the sample, target, and downstream analytical method. Common options include PBS, PBS-X, Tris, and DMEM.

Related Resources

Need Help Selecting Consumables?

Contact InnovaPrep for assistance selecting Concentration Tips, CPT Matrix Prefilters, Upstream Clarification Filters, and Elution Fluids for your specific workflow.

 

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